Introduction

Aloe Vera has a long history of popular and traditional use. It is used in traditional Indian medicine for constipation, colic, skin problems, intestinal worms and infections. It is also used in Trinidad and Tobago for hypertension, and Mexican Americans use it for the treatment of type 2 diabetes. Chinese medicine is often recommended for the treatment of fungal diseases. In Western society, Aloe Vera is one of the few herbal remedies used in common practice and is widely used in the cosmetic, pharmaceutical and food industries. In terms of health, therapeutic recommendations for local application and oral administration of Aloe Vera products cover a wide range, but few assertions have been screened by clinical investigation. Clinical studies investigating the effects of the Aloe Vera plant include dermatological problems, burns and wounds, constipation and gastrointestinal problems.

Arshad H Rahmani, Yousef H Aldebasi, Sauda Srikar, Amjad A Khan, Salah M Aly

Natural-based products treatment is growing rapidly across the globe due to lower accessibility and side effects. Thus, different plants and products derived therefrom are used in primary treatment and they play an important role in the treatment of diseases by modifying biochemical and molecular pathways. Aloe vera, a juicy cactus species, produces gel and latex that have a therapeutic role in health issues through antioxidant, anti-tumor and anti-inflammatory activities, and also provides a viable alternative approach to the treatment of various types of diseases. This study summarizes the possible mechanism of action and the therapeutic implications of the Aloe vera plant in health, based on modulation activities and other biological activities.

Introduction

Traditional medicine plays an important role in the treatment of different types of diseases. Nowadays, the appeal to complementary medicine and natural products is in rapid growth across the globe, given that they are effective and cheap and have fewer side effects. Different types of medicinal plants and their constituents are used to treat diseases from ancient times. The significance of plants and their constituents in the healing of diseases has been discussed in Ayurveda, Unani and in Chinese medicine, as well as in other religious books. In Islam, plants are considered to have significant value in solving health problems, and Mohamad has recommended various herbs for curing diseases such as Nigella sativa seeds and dates. Past investigators have reported that medicinal plants and their constituents, such as Nigella sativa, dates and curcumin, have played and play an important role in disease prevention by modulation of several activities. However, only a few of the plants and their constituents have been appropriately investigated using animal models in terms of their toxicity / lethal dose and mechanism of action in preventing disease. In this regard, juicy species of Aloe Vera play an important role in healing diseases by modulating various activities. The relevant chemical constituents are vitamins, minerals, enzymes, sugars, anthraquinones, lignins, alicylic acid and saponins, and most constituents seem to have biological significance in healing diseases.